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Nottinghamshire Area Prescribing Committee
Joint Formulary
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.06  Expand sub section  Drugs used in nausea and vertigo
04.06  Expand sub section  Antihistamines
04.06  Expand sub section  Phenothiazines and related drugs
Chlorpromazine
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Formulary
Green
See section 4.2.1
  • May be used in the treatment of hiccup 
  •    
    Droperidol (Xomolix®)
    View adult BNF View SPC online View childrens BNF
    Restricted Drug Restricted
    Red
    Injection 2.5mg/ml
  • For use in PONV.
  • For IV use can be administered undiluted as a slow bolus. 
  • Link  Droperidol risk reduction poster
       
    Levomepromazine
    View adult BNF View SPC online View childrens BNF
    Restricted Drug Restricted
    Green
    -Tablets 25mg. £0.26 per tablet (scored for doses of 12.5mg and can be quartered for doses of 6.25mg)
    -Tablets 6mg. £2.40 per tablet! NUH only (Unlicensed- named patient use only).
    -Injection
  • Palliative care use only
  • Tablets disperse in water if needed. See here for general advice on dispersing tablets.
  • Used to be called methotrimeprazine 
  • Link  End of life guideline available on Nottinghamshire APC site
    Link  Standard anticipatory medicines for end of life care
       
    Prochlorperazine
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    Formulary
    Green

    Tablet, Buccal tablet, Injection (IM route only. Not for IV or SC use.)

     

    • Liquid discontinued 2019.
     
       
    04.06  Expand sub section  Domperidone and metoclopramide
    04.06  Expand sub section  5HT3 antagonists to top
    04.06  Expand sub section  Neurokinin receptor antagonist
    04.06  Expand sub section  Cannabinoid
    04.06  Expand sub section  Hyoscine
    04.06  Expand sub section  Other drugs for Ménière's disease
     ....
     Non Formulary Items
    Perphenazine

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
     
    Trifluoperazine

    View adult BNF View SPC online View childrens BNF
    Non Formulary
    Grey
    See section 4.2.1
     
      
    Key
    note Notes
    Section Title Section Title (top level)
    Section Title Section Title (sub level)
    First Choice Item First Choice item
    Non Formulary Item Non Formulary section
    Restricted Drug
    Restricted Drug
    Unlicensed Drug
    Unlicensed
    Track Changes
    Display tracking information
    click to search medicines.org.uk
    Link to adult BNF
    click to search medicines.org.uk
    Link to children's BNF
    click to search medicines.org.uk
    Link to SPCs
    SMC
    Scottish Medicines Consortium
    Cytotoxic Drug
    Cytotoxic Drug
    CD
    Controlled Drug
    High Cost Medicine
    High Cost Medicine
    Cancer Drugs Fund
    Cancer Drugs Fund
    NHSE
    NHS England
    Homecare
    Homecare
    CCG
    CCG

    Traffic Light Status Information

    Status Description

    Grey

    Grey / Non-Formulary: Medicines, which the Nottinghamshire APC has actively reviewed and does not recommend for use at present due to limited clinical and/or cost effective data.
    Grey / Non-Formulary (undergoing assessment): Work is ongoing and will be reviewed at a future APC meeting.
    Grey / Non-Formulary (no formal assessment): APC has not formally reviewed this medicine or indication because it had never been requested for formulary inclusion. Often used for drugs new to market.
      

    Red

    Medicines which should normally be prescribed by specialists only. eg hospital only.
    For patients already receiving prescriptions in primary care - continue. No new patients to receive prescriptions in primary care.
      

    Amber 1

    Medicines that should be initiated by a specialist and prescribed by primary care prescribers only under a shared care protocol, once the patient has been stabilised.
    Prior agreement must be obtained by the specialist from the primary care provider before prescribing responsibility is transferred. The shared care protocol must have been agreed by the relevant secondary care trust Drugs and Therapeutics Committee(s) (DTC) and approved by the Nottinghamshire APC.
      

    Amber 2

    Medicines suitable to be prescribed in primary care / general practice after specialist* recommendation or initiation.
    A supporting prescribing guideline may be requested which must have been agreed by the relevant secondary care trust DTCs and approved by the Nottinghamshire APC.
    *Specialist is defined by the APC as a clinician who has undertaken an appropriate formal qualification or recognised training programme within the described area of practice
      

    Amber 3

    Primary care/ non specialist may initiate as per APC guideline.
    The supporting prescribing guideline must have been agreed by the relevant secondary care trust D&TC(s) and approved by the Nottinghamshire APC.
      

    Green

    Medicines suitable for routine use within primary care.
    Can be initiated within primary care within their licensed indication, in accordance with nationally recognised formularies, for example the BNF, BNF for Children, Medicines for Children or Palliative Care Formulary. Primary care prescribers take full responsibility for prescribing.   

    OTC

      

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